Enschede is home to some of the best clubs where you can experience an electrifying nightlife. Aspen Valley Enschede is a standout, known for its energetic vibe and top-notch DJ performances. Bolke Enschede offers a lively atmosphere with a mix of music genres that keep the crowd dancing all night. Jazzpodium De Tor is perfect for jazz lovers, providing a sophisticated setting with live jazz performances. Concordia Enschede also adds to the city's club scene with its diverse musical events. These clubs ensure that there's something for everyone in Enschede's nightlife.

Enschede has produced several popular local musicians who have made a significant impact on the music scene. Odium is a well-known name, bringing a unique sound that resonates with many fans. JJD is another prominent artist, known for his electronic music that has garnered a substantial following. Thomas Berge has also made waves with his captivating performances and heartfelt music. Additionally, Boray f.k.a Requiem continues to impress with his innovative approach to music. These artists highlight the rich musical talent that Enschede has to offer.

For those who enjoy outdoor live music, Enschede offers some fantastic spots. Vliegveld Twenthe is a prime location, hosting large-scale outdoor concerts and festivals that attract music lovers from all over. Recreatiepark Het Rutbeek is another excellent venue, providing a scenic backdrop for various live music events. The Military Airbase Twenthe also serves as a unique setting for outdoor concerts, adding a historical touch to the musical experience. These venues make Enschede a great destination for enjoying live music in the open air.