For those seeking the best clubs in Cairo, the city offers a variety of top-notch venues. Cairo Jazz Club is a must-visit, renowned for its dynamic live music and DJ sets. Nineteen Twenty Five is another hotspot, offering a chic environment and a mix of electronic and live music. 24K stands out for its luxurious setting and vibrant nightlife. Rai Club Cairo is also a favorite among locals and tourists alike, known for its lively atmosphere and diverse music genres.

Cairo boasts a rich pool of talented local musicians who have made significant contributions to the music scene. Tamer Hosny is a household name, known for his versatile singing and acting career. Amr Diab, often referred to as the 'Father of Mediterranean Music,' has a massive following both locally and internationally. Sherine is celebrated for her powerful voice and emotional performances. Additionally, Cairokee has gained immense popularity for their unique blend of rock and Egyptian folk music.

Outdoor live music in Cairo can be enjoyed at several fantastic spots. The Clubhouse Uptown offers a great outdoor setting with regular live performances. Al-Azhar Park is another excellent venue, providing a beautiful backdrop for concerts and cultural events. El Sawy Culturewheel frequently hosts outdoor music events, attracting a diverse crowd. Darb 1718 is also a notable mention, known for its vibrant cultural scene and open-air performances.